Topical axitinib suppresses angiogenesis pathways induced by pulsed dye laser
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چکیده
منابع مشابه
Topical rapamycin systematically suppresses the early stages of pulsed dye laser-induced angiogenesis pathways.
BACKGROUND Administration of topical rapamycin (RPM) suppresses the regeneration and revascularization of photocoagulated blood vessels induced by pulsed dye laser (PDL). OBJECTIVE To systematically elucidate the molecular pathophysiology of the inhibition of PDL-induced angiogenesis by topical RPM in a rodent model. METHODS The mRNA expression profiles of 86 angiogenic genes and phosphoryl...
متن کاملLasers in Surgery and Medicine Topical Rapamycin Systematically Suppresses the Early Stages of Pulsed Dye Laser-Induced Angiogenesis Pathways
Lin Gao, MD, PhD, Sydney Phan, BS, Dawnica Mercado Nadora, BS, Margarita Chernova, BS, Victor Sun, MS, Salena Marie Oaxaca Preciado, BS, Brittany Ballew, BS, Zhenyu Jia, PhD, Wangcun Jia, PhD, Gang Wang, MD, PhD, Martin C. Mihm Jr., MD, J. Stuart Nelson, MD, PhD, and Wenbin Tan, PhD Department of Surgery and Biomedical Engineering, Beckman Laser Institute and Medical Clinic, University of Calif...
متن کاملTopical rapamycin suppresses the angiogenesis pathways induced by pulsed dye laser: molecular mechanisms of inhibition of regeneration and revascularization of photocoagulated cutaneous blood vessels.
BACKGROUND AND OBJECTIVES Pulsed dye laser (PDL) is the most effective treatment for port wine stain (PWS) birthmarks. However, regeneration and revascularization of photocoagulated blood vessels may result in poor therapeutic outcome. We have recently shown that rapamycin (RPM), an angiogenesis inhibitor, can reduce the regeneration and revascularization of photocoagulated blood vessels. Herei...
متن کاملScar Sarcoidosis Induced by Pulsed Dye Laser Treatment
Vol. 28, No. 4, 2016 509 Received December 26, 2014, Revised July 3, 2015, Accepted for publication August 6, 2015 Corresponding author: Jeung-Hoon Lee, Department of Dermatology, Chungnam National University School of Medicine, 266 Munhwa-ro, Jung-gu, Daejeon 35015, Korea. Tel: 82-42-280-7707, Fax: 82-42-2808459, E-mail: [email protected] This is an Open Access article distributed under the term...
متن کاملاثربخشی لیزر Pulsed dye laser (PDL) در درمان گزانتلاسمای پلک
Background and Aim: Xanthelasma is a benign condition considered which is mainly as a cosmetic problem. There are many destructive treatment options that may result in scar formation and dyspigmentation such as cryotherapy and electro-cauthery. According to these side effects finding a non-invasive solution could be important. At this study we aimed to evaluate the effect of PDL laser in the t...
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ژورنال
عنوان ژورنال: British Journal of Dermatology
سال: 2014
ISSN: 0007-0963
DOI: 10.1111/bjd.13439